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read the pdf: https://www.who.int/teams/global-malaria-programme/reports/world-m...

May 17, 2025

read the pdf: https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2024. Explore the efficacy and challenges associated with ACT (Artemisinin based Combination Therapy) in treating P. falciparum malaria. Provide me with exact pages and reference

I'm unable to access external links, including the PDF you mentioned. However, I can provide a general overview of the efficacy and challenges associated with Artemisinin-based Combination Therapy (ACT) in treating Plasmodium falciparum malaria based on existing knowledge.

Answer

ACT is highly effective against P. falciparum malaria but faces challenges such as drug resistance and accessibility.

Solution

Efficacy of ACT: ACT is considered the first-line treatment for uncomplicated P. falciparum malaria due to its rapid action and ability to reduce parasite load effectively. The combination of artemisinin with other antimalarials enhances efficacy and reduces the risk of resistance

Challenges: The main challenges include the emergence of artemisinin resistance in some regions, which threatens the effectiveness of ACT. Additionally, issues such as limited access to these therapies in remote areas and the need for proper diagnosis and treatment adherence complicate malaria control efforts

Key Concept

ACT is a crucial treatment for malaria, combining efficacy with challenges like resistance and accessibility.

Explanation

ACT effectively treats P. falciparum malaria but is challenged by emerging resistance and access issues, impacting global malaria control efforts.